League Leaders - Offense
| Passing Yards | Complete List | |
Bryce Young
|
1. Bryce Young, CAR | 5123 |
| 2. C.J. Stroud, BUF | 4522 | |
| 3. Will Levis, TEN | 4156 | |
| 4. Anthony Richardson, IND | 3809 | |
| 5. Aidan O'Connell, LV | 3781 | |
| Rushing Yards | Complete List | |
Jahmyr Gibbs
|
1. Jahmyr Gibbs, DET | 1971 |
| 2. Bijan Robinson, ATL | 1170 | |
| 3. De'Von Achane, MIA | 929 | |
| 4. Israel Abanikanda, NYJ | 612 | |
| 5. Anthony Richardson, IND | 484 | |
| Receiving Yards | Complete List | |
Jonathan Mingo
|
1. Jonathan Mingo, CAR | 1548 |
| 2. Jayden Reed, GB | 1195 | |
| 3. Tank Dell, HOU | 1110 | |
| 4. Puka Nacua, LAR | 1062 | |
| 5. Jaxon Smith-Njigba, SEA | 952 | |
League Leaders - Defense
| Tackles | Complete List | |
Jack Campbell
|
1. Jack Campbell, DET | 71 |
| 2. Christian Gonzalez, NE | 67 | |
| 3. Mekhi Blackmon, MIN | 61 | |
| 4. Julius Brents, IND | 61 | |
| 5. Devon Witherspoon, SEA | 57 | |
| Sacks | Complete List | |
Will McDonald IV
|
1. Will McDonald IV, NYJ | 9 |
| 2. Jalen Carter, PHI | 7 | |
| 3. Lukas Van Ness, GB | 6 | |
| 4. Bryan Bresee, NO | 5 | |
| 5. Tyree Wilson, LV | 5 | |
| Interceptions | Complete List | |
Brandon Hill
|
1. Brandon Hill, JAX | 11 |
| 2. DJ Turner II, CIN | 11 | |
| 3. Devon Witherspoon, SEA | 9 | |
| 4. Jakorian Bennett, LV | 6 | |
| 5. JL Skinner, LV | 5 | |