League Leaders - Offense
| Passing Yards | Complete List | |
| Rushing Yards | Complete List | |
Sergio Duncan
|
1. Sergio Duncan, GB | 169 |
| 2. Darren Queen, PHI | 117 | |
| 3. Sterling Bass, TEN | 79 | |
| 4. Darryl Bradley, PHI | 31 | |
| 5. Mike Etienne, ARI | 28 | |
| Receiving Yards | Complete List | |
Leo McLean
|
1. Leo McLean, BUF | 1899 |
| 2. Kyle Brady, NYJ | 918 | |
| 3. Darryl Bradley, PHI | 844 | |
| 4. Andrew Murphy, JAX | 583 | |
| 5. Bo Richards, WAS | 473 | |
League Leaders - Defense
| Tackles | Complete List | |
Malcolm Campbell
|
1. Malcolm Campbell, BUF | 50 |
| 2. Nathan Lowery, SEA | 49 | |
| 3. Jason Peoples, JAX | 44 | |
| 4. Jacquez Hardesty, NYJ | 44 | |
| 5. Marquise Bowens, PIT | 27 | |
| Sacks | Complete List | |
|
Roderick Cobb
|
1. Roderick Cobb, NE | 3 |
| 2. Bryce Middleton, CIN | 2 | |
| 3. Christopher Jones, ATL | 1 | |
| 4. Mike Hurts, DET | 1 | |
| 5. Frank Atkins, ARI | 1 | |
| Interceptions | Complete List | |
Jason Peoples
|
1. Jason Peoples, JAX | 3 |
| 2. Malcolm Campbell, BUF | 3 | |
| 3. Pop King, HOU | 2 | |
| 4. Jacquez Hardesty, NYJ | 1 | |
| 5. DeSean Hall, WAS | 1 | |