League Leaders - Offense
| Passing Yards | Complete List | |
Joe Burrow
|
1. Joe Burrow, CIN | 5336 |
| 2. Dak Prescott, DAL | 4785 | |
| 3. C.J. Stroud, HOU | 4598 | |
| 4. Tua Tagovailoa, MIA | 4562 | |
| 5. Bryce Young, NO | 4450 | |
| Rushing Yards | Complete List | |
Jonathan Taylor
|
1. Jonathan Taylor, IND | 1938 |
| 2. Bijan Robinson, ATL | 1797 | |
| 3. Breece Hall, MIN | 1506 | |
| 4. Jimmy Browning, NE | 1454 | |
| 5. Josh Jacobs, PHI | 1337 | |
| Receiving Yards | Complete List | |
Leo McLean
|
1. Leo McLean, BUF | 1899 |
| 2. Ja'Marr Chase, CIN | 1870 | |
| 3. Mecole Hardman Jr, HOU | 1458 | |
| 4. Jaylen Waddle, MIA | 1327 | |
| 5. Marvin Harrison Jr, TEN | 1310 | |
League Leaders - Defense
| Tackles | Complete List | |
Daiyan Henley
|
1. Daiyan Henley, LAC | 103 |
| 2. Drew Sanders, DEN | 100 | |
| 3. Davon Skinner, ARI | 96 | |
| 4. Darren Bowman, GB | 91 | |
| 5. Baron Browning, DEN | 86 | |
| Sacks | Complete List | |
Nolan Smith Jr
|
1. Nolan Smith Jr, PHI | 18 |
| 2. Maxx Crosby, DET | 16 | |
| 3. Trey Hendrickson, CIN | 15 | |
| 4. Danielle Hunter, MIN | 15 | |
| 5. Bradley Chubb, ATL | 14 | |
| Interceptions | Complete List | |
Payton Wilson
|
1. Payton Wilson, PHI | 9 |
| 2. Derek Stingley Jr, HOU | 8 | |
| 3. Kyle Hamilton, BAL | 7 | |
| 4. Amani Hooker, TEN | 7 | |
| 5. Dante McCarthy, NYG | 7 | |