League Leaders - Offense
| Passing Yards | Complete List | |
Ray Greene IV
|
1. Ray Greene IV, NE | 4761 |
| 2. Jason Paulson, CAR | 4050 | |
| 3. Thad Adams, SEA | 3875 | |
| 4. Max Duggan, KC | 3800 | |
| 5. Ahmad Smith, CIN | 1588 | |
| Rushing Yards | Complete List | |
Keanu Isles
|
1. Keanu Isles, NE | 1514 |
| 2. Louis Meekins, SEA | 978 | |
| 3. Marshawn Lynch Jr., CIN | 641 | |
| 4. Glen Smith, CAR | 609 | |
| 5. Jason Paulson, CAR | 142 | |
| Receiving Yards | Complete List | |
Trey Rogeezy
|
1. Trey Rogeezy, CIN | 2969 |
| 2. Aubrey Osborne, JAX | 2254 | |
| 3. Austen Logan Jr, IND | 1834 | |
| 4. Romeo Rodgers, LV | 1487 | |
| 5. Darrell Cox, KC | 1456 | |
League Leaders - Defense
| Tackles | Complete List | |
Hakeem Walters
|
1. Hakeem Walters, ATL | 33 |
| 2. Braxton Price, CIN | 31 | |
| 3. Enn Krizzy, BAL | 30 | |
| 4. Byron Ware, SF | 29 | |
| 5. Tyquan Lynch, NO | 29 | |
| Sacks | Complete List | |
Bret Strong
|
1. Bret Strong, CIN | 8 |
| 2. Braxton Price, CIN | 5 | |
| 3. Adrian Street, NO | 5 | |
| 4. Ahmad Graham, NYG | 3 | |
| 5. Junior Hatcher, KC | 3 | |
| Interceptions | Complete List | |
Ameer Williamson
|
1. Ameer Williamson, CHI | 6 |
| 2. Rashaad Porter, CHI | 6 | |
| 3. Tyquan Lynch, NO | 4 | |
| 4. Enn Krizzy, BAL | 4 | |
| 5. Hakeem Walters, ATL | 4 | |