League Leaders - Offense
| Passing Yards | Complete List | |
Lyle McCollum
|
1. Lyle McCollum, DET | 434 |
| 2. Dak Prescott, DAL | 379 | |
| 3. Desmond Ridder, ATL | 367 | |
| 4. Matt Cooper, NE | 268 | |
| 5. Jonathan Monroe, SEA | 260 | |
| Rushing Yards | Complete List | |
Kenneth Walker III
|
1. Kenneth Walker III, SEA | 150 |
| 2. Trae Landry, NE | 86 | |
| 3. Ezekiel Elliott, DAL | 84 | |
| 4. Malik Willis, NYJ | 84 | |
| 5. D'Andre Swift, DET | 77 | |
| Receiving Yards | Complete List | |
Jameson Williams
|
1. Jameson Williams, DET | 224 |
| 2. CeeDee Lamb, DAL | 143 | |
| 3. D.K. Metcalf, SEA | 120 | |
| 4. George Kittle, SF | 110 | |
| 5. Joe Stephenson, NE | 105 | |
League Leaders - Defense
| Tackles | Complete List | |
Divine Deablo
|
1. Divine Deablo, WAS | 9 |
| 2. Marcus Jones, ATL | 7 | |
| 3. Deion Jones, ATL | 5 | |
| 4. Mike Edwards, NYJ | 5 | |
| 5. Al Morgan, NE | 5 | |
| Sacks | Complete List | |
Montez Sweat
|
1. Montez Sweat, ATL | 2 |
| 2. Dre Greenlaw, SF | 1 | |
| 3. Chase Young, WAS | 1 | |
| 4. Drake Jackson, SF | 1 | |
| 5. DeMarcus Lawrence, DAL | 1 | |
| Interceptions | Complete List | |
Sean Murphy-Bunting
|
1. Sean Murphy-Bunting, WAS | 1 |
| 2. Byron Jones, SEA | 1 | |
| 3. Divine Deablo, WAS | 1 | |
| 4. Jeff Okudah, DET | 1 | |
| 5. Dorian Adams, SF | 1 | |