League Leaders - Offense
| Passing Yards | Complete List | |
Caleb Williams
|
1. Caleb Williams, HOU | 4120 |
| 2. Drake Maye, IND | 3373 | |
| 3. Quinn Ewers, NYJ | 169 | |
| 4. Conner Bazelak, NYG | 161 | |
| 5. Carson Beck, CIN | 144 | |
| Rushing Yards | Complete List | |
Donovan Edwards
|
1. Donovan Edwards, LAR | 402 |
| 2. Braelon Allen, TEN | 380 | |
| 3. Will Shipley, NE | 223 | |
| 4. Caleb Williams, HOU | 150 | |
| 5. Alton McCaskill, NE | 124 | |
| Receiving Yards | Complete List | |
Marvin Harrison Jr
|
1. Marvin Harrison Jr, ATL | 916 |
| 2. Xavier Worthy, MIN | 886 | |
| 3. Brock Bowers, LAR | 549 | |
| 4. Gavin Bartholomew, DET | 254 | |
| 5. Jack Bech, ATL | 233 | |
League Leaders - Defense
| Tackles | Complete List | |
Sage Ryan
|
1. Sage Ryan, KC | 84 |
| 2. Scooby Williams, TB | 83 | |
| 3. Eric Gentry, HOU | 69 | |
| 4. Billy Bowman, DAL | 62 | |
| 5. Jason Marshall Jr., NE | 58 | |
| Sacks | Complete List | |
Leonard Taylor
|
1. Leonard Taylor, LV | 4 |
| 2. Xavian Sorey Jr., MIN | 4 | |
| 3. Keeshawn Silver, BUF | 4 | |
| 4. Shemar Turner, CIN | 4 | |
| 5. Tunmise Adeleye, LAR | 3 | |
| Interceptions | Complete List | |
Jason Marshall Jr.
|
1. Jason Marshall Jr., NE | 4 |
| 2. Scooby Williams, TB | 2 | |
| 3. Denzel Burke, WAS | 2 | |
| 4. Justin Walley, NYJ | 2 | |
| 5. Ga'Quincy McKinstry, DEN | 2 | |