League Leaders - Offense
| Passing Yards | Complete List | |
Jon Snow The Bast
|
1. Jon Snow The Bast, DAL | 3869 |
| 2. Jalen Hurts, PHI | 3544 | |
| 3. Carson Wentz, WAS | 2762 | |
| 4. Lamar Jackson, BAL | 2613 | |
| 5. Bryce Young, SEA | 2589 | |
| Rushing Yards | Complete List | |
Tyrion Davis-Price
|
1. Tyrion Davis-Price, DAL | 1364 |
| 2. Dalvin Cook, MIN | 1126 | |
| 3. Damien Harris, NE | 1090 | |
| 4. Kenneth Walker III, SEA | 865 | |
| 5. Joe Mixon, CIN | 862 | |
| Receiving Yards | Complete List | |
Jameson Williams
|
1. Jameson Williams, DET | 1407 |
| 2. A.J. Brown, PHI | 1339 | |
| 3. CeeDee Lamb, DAL | 1213 | |
| 4. Tyquan Thornton, NE | 1178 | |
| 5. Keenan Allen, LAC | 1167 | |
League Leaders - Defense
| Tackles | Complete List | |
Jordyn Brooks
|
1. Jordyn Brooks, SEA | 46 |
| 2. Matt Milano, BUF | 45 | |
| 3. Tremaine Edmunds, SEA | 44 | |
| 4. Kyzir White, PHI | 42 | |
| 5. Damone Clark, DAL | 41 | |
| Sacks | Complete List | |
Maxx Crosby
|
1. Maxx Crosby, LV | 13 |
| 2. Micah Parsons, DAL | 12 | |
| 3. Trey Hendrickson, CIN | 11 | |
| 4. Josh Sweat, PHI | 11 | |
| 5. Von Miller, BUF | 9 | |
| Interceptions | Complete List | |
Trevon Diggs
|
1. Trevon Diggs, DAL | 10 |
| 2. Kyle Dugger, NE | 10 | |
| 3. Donte Jackson, PHI | 10 | |
| 4. Vonn Bell, CIN | 8 | |
| 5. Kelvin Joseph, DAL | 7 | |