League Leaders - Offense
| Passing Yards | Complete List | |
K.J. Jefferson
|
1. K.J. Jefferson, ATL | 768 |
| 2. J.J. McCarthy, DET | 599 | |
| 3. Bo Nix, NYJ | 542 | |
| 4. Jordan Travis, DEN | 520 | |
| 5. Caleb Williams, SEA | 498 | |
| Rushing Yards | Complete List | |
TreVeyon Henderson
|
1. TreVeyon Henderson, CAR | 146 |
| 2. Braelon Allen, LAR | 113 | |
| 3. Alex Stanley, JAX | 91 | |
| 4. Mar'Keise Irving, ARI | 59 | |
| 5. Caleb Williams, SEA | 46 | |
| Receiving Yards | Complete List | |
Xavier Worthy
|
1. Xavier Worthy, ATL | 365 |
| 2. Dorian Singer, DET | 182 | |
| 3. Marvin Harrison Jr., STL | 175 | |
| 4. Brock Bowers, ORL | 109 | |
| 5. Malik Nabers, GB | 108 | |
League Leaders - Defense
| Tackles | Complete List | |
Josh Wallace
|
1. Josh Wallace, LAR | 12 |
| 2. Jeremiah Trotter Jr., TEN | 11 | |
| 3. Malachi Moore, NYJ | 10 | |
| 4. Decorian Patterson, CAR | 7 | |
| 5. Jason Marshall Jr., ATL | 6 | |
| Sacks | Complete List | |
Carlos Cheeks
|
1. Carlos Cheeks, LAR | 2 |
| 2. Jack Sawyer, DET | 1 | |
| 3. Tyleik Williams, KC | 1 | |
| 4. Dontay Corleone, DEN | 0 | |
| 5. Laiatu Latu, MIN | 0 | |
| Interceptions | Complete List | |
Decorian Patterson
|
1. Decorian Patterson, CAR | 1 |
| 2. Jason Marshall Jr., ATL | 1 | |
| 3. Tyler Nubin, ARI | 1 | |
| 4. Barrett Carter, CLE | 1 | |
| 5. Nate Wiggins, CLE | 1 | |