League Leaders - Offense
| Passing Yards | Complete List | |
K.J. Jefferson
|
1. K.J. Jefferson, ATL | 768 |
| 2. Jordan Love, GB | 678 | |
| 3. J.J. McCarthy, DET | 599 | |
| 4. Bo Nix, NYJ | 542 | |
| 5. Jordan Travis, DEN | 520 | |
| Rushing Yards | Complete List | |
Aaron Jones
|
1. Aaron Jones, GB | 287 |
| 2. Bijan Robinson, ATL | 252 | |
| 3. Nick Chubb, CLE | 224 | |
| 4. Dameon Pierce, HST | 209 | |
| 5. Cam Akers, MIN | 205 | |
| Receiving Yards | Complete List | |
Xavier Worthy
|
1. Xavier Worthy, ATL | 365 |
| 2. Jameson Williams, DET | 253 | |
| 3. Garrett Wilson, NYJ | 206 | |
| 4. Elijah Moore, CLE | 199 | |
| 5. Aaron Jones, GB | 187 | |
League Leaders - Defense
| Tackles | Complete List | |
Patrick Queen
|
1. Patrick Queen, BAL | 18 |
| 2. Leighton Vander Esch, DAL | 17 | |
| 3. Christian Gonzalez, NE | 15 | |
| 4. Troy Andersen, ATL | 15 | |
| 5. Germaine Pratt, STL | 14 | |
| Sacks | Complete List | |
Azeez Ojulari
|
1. Azeez Ojulari, NYG | 4 |
| 2. Nick Bosa, SF | 4 | |
| 3. George Karlaftis, KC | 2 | |
| 4. Nik Bonitto, DEN | 2 | |
| 5. DeMarcus Lawrence, DAL | 2 | |
| Interceptions | Complete List | |
Andre Cisco
|
1. Andre Cisco, JAX | 4 |
| 2. Jonathan Owens, DEN | 3 | |
| 3. Joey Porter Jr, ORL | 3 | |
| 4. Daiyan Henley, LAC | 2 | |
| 5. Donte Jackson, DEN | 2 | |