League Leaders - Offense
| Passing Yards | Complete List | |
Desmond Ridder
|
1. Desmond Ridder, ATL | 2531 |
| 2. Sam Howell, WAS | 2424 | |
| 3. Matt Corral, CAR | 2247 | |
| 4. Kenny Pickett, PIT | 1677 | |
| 5. Malik Willis, TEN | 25 | |
| Rushing Yards | Complete List | |
Kenneth Walker III
|
1. Kenneth Walker III, SEA | 590 |
| 2. Breece Hall, NYJ | 458 | |
| 3. Dameon Pierce, HOU | 403 | |
| 4. Trestan Ebner, CHI | 255 | |
| 5. Desmond Ridder, ATL | 226 | |
| Receiving Yards | Complete List | |
Drake London
|
1. Drake London, ATL | 655 |
| 2. Garrett Wilson, NYJ | 586 | |
| 3. Velus Jones Jr, CHI | 511 | |
| 4. Trey McBride, ARI | 453 | |
| 5. Christian Watson, GB | 433 | |
League Leaders - Defense
| Tackles | Complete List | |
Jaquan Brisker
|
1. Jaquan Brisker, CHI | 37 |
| 2. Nick Cross, IND | 32 | |
| 3. Tariq Woolen, SEA | 29 | |
| 4. Devin Lloyd, JAX | 28 | |
| 5. Kalon Barnes, MIA | 27 | |
| Sacks | Complete List | |
Kayvon Thibodeaux
|
1. Kayvon Thibodeaux, NYG | 5 |
| 2. Amare Barno, CAR | 4 | |
| 3. Aidan Hutchinson, DET | 3 | |
| 4. Channing Tindall, MIA | 2 | |
| 5. Travon Walker, JAX | 2 | |
| Interceptions | Complete List | |
Tony Adams
|
1. Tony Adams, NYJ | 6 |
| 2. Tariq Castro-Fields, WAS | 5 | |
| 3. Channing Tindall, MIA | 5 | |
| 4. Jaquan Brisker, CHI | 4 | |
| 5. Nazeeh Johnson, PIT | 4 | |