League Leaders - Offense
| Passing Yards | Complete List | |
Joe Burrow
|
1. Joe Burrow, CIN | 3998 |
| 2. Malik Willis, LV | 3982 | |
| 3. C.J. Stroud, HOU | 3852 | |
| 4. Patrick Mahomes, KC | 3704 | |
| 5. Malik Cunningham, MIN | 3637 | |
| Rushing Yards | Complete List | |
De'Von Achane
|
1. De'Von Achane, MIA | 1702 |
| 2. Jonathan Taylor, IND | 1577 | |
| 3. Breece Hall, NYJ | 1548 | |
| 4. Christian McCaffrey, LAC | 1405 | |
| 5. Saquon Barkley, NYG | 1393 | |
| Receiving Yards | Complete List | |
Chris Olave
|
1. Chris Olave, NO | 1464 |
| 2. Tyreke Hail, MIA | 1273 | |
| 3. Tyreek Hill, MIA | 1238 | |
| 4. Diontae Johnson, JAX | 1184 | |
| 5. A.J. Brown, PHI | 1171 | |
League Leaders - Defense
| Tackles | Complete List | |
Drew Sanders
|
1. Drew Sanders, DEN | 103 |
| 2. Azeez Al-Shaair, TEN | 102 | |
| 3. Channing Foster, DAL | 102 | |
| 4. Fred Warner, SF | 95 | |
| 5. Isaac Walden, JAX | 90 | |
| Sacks | Complete List | |
Myles Garrett
|
1. Myles Garrett, CLE | 18 |
| 2. Joey Bosa, LAC | 18 | |
| 3. Will Anderson Jr, HOU | 16 | |
| 4. Aaron Donald, LAR | 15 | |
| 5. Josh Uche, LAC | 11 | |
| Interceptions | Complete List | |
Jevon Holland
|
1. Jevon Holland, MIA | 6 |
| 2. Derek Stingley Jr, HOU | 6 | |
| 3. Isaiah Simmons, NYG | 6 | |
| 4. Jaire Alexander, GB | 6 | |
| 5. Daniel Conley, GB | 6 | |