League Leaders - Offense
| Passing Yards | Complete List | |
Drake Maye
|
1. Drake Maye, NE | 4280 |
| 2. Jayden Daniels, WAS | 2458 | |
| 3. Caleb Williams, CHI | 2330 | |
| 4. J.J. McCarthy, MIN | 1938 | |
| 5. Bo Nix, DEN | 1812 | |
| Rushing Yards | Complete List | |
MarShawn Lloyd
|
1. MarShawn Lloyd, OAK | 455 |
| 2. Trey Benson, ARI | 435 | |
| 3. Jonathon Brooks, CAR | 345 | |
| 4. Drake Maye, NE | 277 | |
| 5. Ray Davis, BUF | 248 | |
| Receiving Yards | Complete List | |
Tyler Harrell
|
1. Tyler Harrell, OAK | 1331 |
| 2. Brock Bowers, OAK | 655 | |
| 3. Roman Wilson, PIT | 574 | |
| 4. Malik Nabers, NYG | 568 | |
| 5. Ladd McConkey, SDG | 558 | |
League Leaders - Defense
| Tackles | Complete List | |
Nate Wiggins
|
1. Nate Wiggins, BAL | 35 |
| 2. Tykee Smith, TB | 29 | |
| 3. Javon Bullard, GB | 28 | |
| 4. Tyler Nubin, NYG | 24 | |
| 5. Junior Colson, SDG | 23 | |
| Sacks | Complete List | |
Dallas Turner
|
1. Dallas Turner, MIN | 8 |
| 2. Byron Murphy II, SEA | 7 | |
| 3. Edgerrin Cooper, GB | 4 | |
| 4. Adisa Isaac, OAK | 4 | |
| 5. Darius Robinson, ARI | 2 | |
| Interceptions | Complete List | |
|
Nate Wiggins
|
1. Nate Wiggins, BAL | 9 |
| 2. Tyler Nubin, NYG | 3 | |
| 3. Junior Colson, SDG | 3 | |
| 4. Max Melton, ARI | 2 | |
| 5. Cole Bishop, BUF | 2 | |