League Leaders - Offense
| Passing Yards | Complete List | |
Drake Maye
|
1. Drake Maye, NE | 4280 |
| 2. Joe Burrow, CIN | 3787 | |
| 3. Jared Goff, DET | 3510 | |
| 4. C.J. Stroud, HOU | 3308 | |
| 5. Josh Allen, BUF | 3117 | |
| Rushing Yards | Complete List | |
Christian McCaffrey
|
1. Christian McCaffrey, SF | 1249 |
| 2. Joe Mixon, HOU | 1133 | |
| 3. Kenneth Walker III, SEA | 1103 | |
| 4. Gus Edwards, SDG | 1017 | |
| 5. Lamar Jackson, BAL | 906 | |
| Receiving Yards | Complete List | |
DeVonta Smith
|
1. DeVonta Smith, PHI | 1448 |
| 2. Jameson Williams, DET | 1335 | |
| 3. Tyler Harrell, OAK | 1331 | |
| 4. Ja'Marr Chase, CIN | 1092 | |
| 5. Christian Watson, GB | 976 | |
League Leaders - Defense
| Tackles | Complete List | |
Kaden Elliss
|
1. Kaden Elliss, ATL | 47 |
| 2. Shaq Thompson, CAR | 47 | |
| 3. Alex Singleton, DEN | 46 | |
| 4. Kyle Hamilton, BAL | 43 | |
| 5. Xavier McKinney, GB | 42 | |
| Sacks | Complete List | |
Micah Parsons
|
1. Micah Parsons, DAL | 13 |
| 2. Josh Uche, NE | 13 | |
| 3. Nick Bosa, SF | 10 | |
| 4. Will Anderson Jr, HOU | 9 | |
| 5. Dallas Turner, MIN | 8 | |
| Interceptions | Complete List | |
Nate Wiggins
|
1. Nate Wiggins, BAL | 9 |
| 2. Fred Warner, SF | 7 | |
| 3. Patrick Peterson, JAX | 7 | |
| 4. John Johnson III, LAR | 7 | |
| 5. Taron Johnson, BUF | 7 | |