League Leaders - Offense
| Passing Yards | Complete List | |
CJ Stroud
|
1. CJ Stroud, IND | 578 |
| 2. Bryce Young, MIN | 475 | |
| 3. Sammy Brewer, ARI | 180 | |
| 4. Bernie McManus, NO | 78 | |
| Rushing Yards | Complete List | |
|
CJ Stroud
|
1. CJ Stroud, IND | 73 |
| 2. Montell Hillman, MIN | 39 | |
| 3. Richard Cooks, NE | 22 | |
| 4. Kyle Peterson, GB | 12 | |
| 5. Manny Monroe, BAL | 9 | |
| Receiving Yards | Complete List | |
Lance Flowers
|
1. Lance Flowers, CAR | 214 |
| 2. Marc Knowles, CIN | 146 | |
| 3. Steven Cunningham, CHI | 138 | |
| 4. Kyle Peterson, GB | 132 | |
| 5. Shaquille Roth, NYJ | 124 | |
League Leaders - Defense
| Tackles | Complete List | |
Will Anderson
|
1. Will Anderson, HOU | 5 |
| 2. Glenn Harden, IND | 5 | |
| 3. Jalen Stokes, LAC | 5 | |
| 4. Malik Irving, LV | 4 | |
| 5. Dwayne Thompson, TB | 4 | |
| Sacks | Complete List | |
|
Will Anderson
|
1. Will Anderson, HOU | 2 |
| 2. Jalen Stokes, LAC | 2 | |
| 3. DeAndre Miner, CLE | 2 | |
| 4. De'Joshua Edwards, DAL | 1 | |
| 5. Tommy Stapleton, CHI | 0 | |
| Interceptions | Complete List | |
De'Joshua Edwards
|
1. De'Joshua Edwards, DAL | 4 |
| 2. Daniel Charles, PHI | 3 | |
| 3. Harvey Reese, DAL | 2 | |
| 4. Nick Perriman, CLE | 2 | |
| 5. Dwayne Thompson, TB | 1 | |