League Leaders - Offense
| Passing Yards | Complete List | |
Joe Burrow
|
1. Joe Burrow, CIN | 707 |
| 2. CJ Stroud, IND | 578 | |
| 3. Justin Fields, CHI | 515 | |
| 4. Davis Mills, HOU | 514 | |
| 5. Bryce Young, MIN | 475 | |
| Rushing Yards | Complete List | |
Tony Pollard
|
1. Tony Pollard, DAL | 220 |
| 2. Leonard Fournette, TB | 213 | |
| 3. Aaron Jones, GB | 197 | |
| 4. Alvin Kamara, NO | 157 | |
| 5. Isaiah Spiller, CHI | 149 | |
| Receiving Yards | Complete List | |
Ja'Marr Chase
|
1. Ja'Marr Chase, CIN | 298 |
| 2. Nico Collins, HOU | 280 | |
| 3. Daniel Bellinger, NYG | 247 | |
| 4. Justin Jefferson, MIN | 228 | |
| 5. Lance Flowers, CAR | 214 | |
League Leaders - Defense
| Tackles | Complete List | |
Derek Stingley Jr
|
1. Derek Stingley Jr, HOU | 10 |
| 2. Dre Greenlaw, HOU | 9 | |
| 3. Desmond King II, HOU | 8 | |
| 4. Alexander Johnson, NYG | 8 | |
| 5. Chris Wilcox, GB | 8 | |
| Sacks | Complete List | |
Joey Bosa
|
1. Joey Bosa, LAC | 5 |
| 2. Neville Gallimore, DAL | 4 | |
| 3. Myles Garrett, CLE | 3 | |
| 4. Randy Gregory, DEN | 3 | |
| 5. Justin Jones, CHI | 2 | |
| Interceptions | Complete List | |
Justin Simmons
|
1. Justin Simmons, DEN | 6 |
| 2. De'Joshua Edwards, DAL | 4 | |
| 3. Devin White, TB | 4 | |
| 4. Taron Johnson, BUF | 3 | |
| 5. Chidobe Awuzie, CIN | 3 | |