League Leaders - Offense
| Passing Yards | Complete List | |
Jalen Milroe
|
1. Jalen Milroe, SEA | 684 |
| 2. Jaxson Dart, NYG | 505 | |
| 3. Cam Ward, TEN | 477 | |
| 4. Dillon Gabriel, CLE | 294 | |
| 5. Shedeur Sanders, CLE | 117 | |
| Rushing Yards | Complete List | |
Dylan Sampson
|
1. Dylan Sampson, CLE | 154 |
| 2. RJ Harvey, DEN | 109 | |
| 3. Kaleb Johnson, PIT | 98 | |
| 4. Cam Skattebo, NYG | 87 | |
| 5. Ashton Jeanty, LV | 65 | |
| Receiving Yards | Complete List | |
Tetairoa McMillan
|
1. Tetairoa McMillan, CAR | 132 |
| 2. Tyler Warren, IND | 132 | |
| 3. Mason Taylor, NYJ | 93 | |
| 4. Colston Loveland, CHI | 71 | |
| 5. RJ Harvey, DEN | 63 | |
League Leaders - Defense
| Tackles | Complete List | |
Jahdae Barron
|
1. Jahdae Barron, DEN | 11 |
| 2. Maxwell Hairston, BUF | 10 | |
| 3. Jihaed Campbell, PHI | 9 | |
| 4. Will Johnson, ARI | 9 | |
| 5. Carson Schwesinger, CLE | 8 | |
| Sacks | Complete List | |
James Pearce Jr
|
1. James Pearce Jr, ATL | 3 |
| 2. Jalon Walker, ATL | 2 | |
| 3. Jihaed Campbell, PHI | 1 | |
| 4. Shemar Stewart, CIN | 1 | |
| 5. Barrett Carter, CIN | 1 | |
| Interceptions | Complete List | |
Trey Amos
|
1. Trey Amos, WAS | 1 |
| 2. Mykel Williams, SF | 0 | |
| 3. Alfred Collins, SF | 0 | |
| 4. Shemar Stewart, CIN | 0 | |
| 5. Kevin Winston Jr, TEN | 0 | |
