League Leaders - Offense
| Passing Yards | Complete List | |
Baker Mayfield
|
1. Baker Mayfield, TB | 1816 |
| 2. Jalen Hurts, PHI | 1704 | |
| 3. Patrick Mahomes, KC | 1698 | |
| 4. Bo Nix, DEN | 1504 | |
| 5. Joe Burrow, CIN | 1488 | |
| Rushing Yards | Complete List | |
Bijan Robinson
|
1. Bijan Robinson, ATL | 504 |
| 2. Breece Hall, NYJ | 465 | |
| 3. Aaron Jones, MIN | 410 | |
| 4. Derrick Henry, BAL | 378 | |
| 5. RJ Harvey, DEN | 375 | |
| Receiving Yards | Complete List | |
Mike Evans
|
1. Mike Evans, TB | 625 |
| 2. Xavier Worthy, KC | 580 | |
| 3. Dallas Goedert, PHI | 568 | |
| 4. Ja'Marr Chase, CIN | 548 | |
| 5. Theo Johnson, NYG | 538 | |
League Leaders - Defense
| Tackles | Complete List | |
Edgerrin Cooper
|
1. Edgerrin Cooper, GB | 38 |
| 2. Mack Wilson Sr, ARI | 35 | |
| 3. Nick Bolton, KC | 32 | |
| 4. Kyzir White, ARI | 31 | |
| 5. Garrett Williams, ARI | 31 | |
| Sacks | Complete List | |
Brian Burns
|
1. Brian Burns, NYG | 7 |
| 2. Aidan Hutchinson, DET | 6 | |
| 3. James Pearce Jr, ATL | 6 | |
| 4. Myles Garrett, CLE | 6 | |
| 5. Jalon Walker, ATL | 6 | |
| Interceptions | Complete List | |
Jessie Bates III
|
1. Jessie Bates III, ATL | 5 |
| 2. Germaine Pratt, CIN | 5 | |
| 3. Jeremiah Owusu-Koramoah, CLE | 4 | |
| 4. Mike Hughes, ATL | 4 | |
| 5. Zack Baun, PHI | 4 | |
