League Leaders - Offense
| Passing Yards | Complete List | |
Ryan Richards
|
1. Ryan Richards, CAR | 2240 |
| 2. Justin Herbert, LAC | 2135 | |
| 3. Sam Howell, SEA | 2086 | |
| 4. Joe Peek, CLE | 2006 | |
| 5. J.J. McCarthy, MIN | 1995 | |
| Rushing Yards | Complete List | |
Rhamondre Stevenson
|
1. Rhamondre Stevenson, LV | 786 |
| 2. Breece Hall, NYJ | 693 | |
| 3. Nick Chubb, CLE | 629 | |
| 4. Travis Etienne Jr, JAX | 622 | |
| 5. Tyjae Spears, TEN | 604 | |
| Receiving Yards | Complete List | |
Anthony Booth
|
1. Anthony Booth, CAR | 802 |
| 2. Nico Collins, HOU | 784 | |
| 3. Jalin Hyatt, NYG | 750 | |
| 4. Jaylen Waddle, MIA | 730 | |
| 5. Christian Watson, SEA | 709 | |
League Leaders - Defense
| Tackles | Complete List | |
Segun Olubi
|
1. Segun Olubi, ARI | 37 |
| 2. Nick Bolton, KC | 36 | |
| 3. Drue Tranquill, KC | 31 | |
| 4. T.J. Edwards, CHI | 31 | |
| 5. Pete Werner, NO | 30 | |
| Sacks | Complete List | |
Leo Chenal
|
1. Leo Chenal, DEN | 9 |
| 2. Aidan Hutchinson, DET | 9 | |
| 3. Micah Parsons, DAL | 8 | |
| 4. YaYa Diaby, TB | 7 | |
| 5. Haason Reddick, NYJ | 7 | |
| Interceptions | Complete List | |
Tariq Woolen
|
1. Tariq Woolen, SEA | 8 |
| 2. Germaine Pratt, CIN | 7 | |
| 3. DaRon Bland, DAL | 6 | |
| 4. Julian Love, SEA | 6 | |
| 5. Mike Sainristil, WAS | 5 | |