League Leaders - Offense
| Passing Yards | Complete List | |
C.J. Stroud
|
1. C.J. Stroud, HOU | 1206 |
| 2. J.J. McCarthy, MIN | 1036 | |
| 3. Michael Penix Jr., ATL | 991 | |
| 4. Spencer Rattler, NO | 986 | |
| 5. Jayden Daniels, WAS | 913 | |
| Rushing Yards | Complete List | |
Bijan Robinson
|
1. Bijan Robinson, ATL | 386 |
| 2. De'Von Achane, MIA | 304 | |
| 3. Jahmyr Gibbs, DET | 300 | |
| 4. Dante Miller, NYG | 275 | |
| 5. Trey Benson, ARI | 270 | |
| Receiving Yards | Complete List | |
Puka Nacua
|
1. Puka Nacua, LAR | 377 |
| 2. Cade Stover, HOU | 331 | |
| 3. Zay Flowers, BAL | 326 | |
| 4. Trey Palmer, TB | 313 | |
| 5. Devin Culp, TB | 272 | |
League Leaders - Defense
| Tackles | Complete List | |
Daiyan Henley
|
1. Daiyan Henley, LAC | 21 |
| 2. Trenton Simpson, BAL | 18 | |
| 3. Edgerrin Cooper, GB | 18 | |
| 4. Kelee Ringo, PHI | 15 | |
| 5. Ivan Pace Jr, MIN | 15 | |
| Sacks | Complete List | |
Dante Stills
|
1. Dante Stills, ARI | 4 |
| 2. Will Anderson Jr, HOU | 3 | |
| 3. Brennan Jackson, LAR | 3 | |
| 4. Kelee Ringo, PHI | 3 | |
| 5. Will McDonald IV, NYJ | 2 | |
| Interceptions | Complete List | |
James Williams
|
1. James Williams, TEN | 4 |
| 2. Tykee Smith, TB | 3 | |
| 3. Nehemiah Pritchett, SEA | 3 | |
| 4. Isaiah Bolden, NE | 3 | |
| 5. Riley Moss, DEN | 3 | |