League Leaders - Offense
| Passing Yards | Complete List | |
Malik Willis
|
1. Malik Willis, TEN | 544 |
| 2. Kenny Pickett, PIT | 463 | |
| 3. Jameson Williams, DET | 1 | |
| 4. Bailey Zappe, NE | 0 | |
| Rushing Yards | Complete List | |
Breece Hall
|
1. Breece Hall, NYJ | 327 |
| 2. Malik Willis, TEN | 191 | |
| 3. Dameon Pierce, HOU | 168 | |
| 4. Tyrion Davis-Price, SF | 120 | |
| 5. Kenneth Walker III, SEA | 83 | |
| Receiving Yards | Complete List | |
Jameson Williams
|
1. Jameson Williams, DET | 304 |
| 2. Jahan Dotson, WAS | 238 | |
| 3. Drake London, ATL | 192 | |
| 4. Jelani Woods, IND | 136 | |
| 5. Garrett Wilson, NYJ | 135 | |
League Leaders - Defense
| Tackles | Complete List | |
Lewis Cine
|
1. Lewis Cine, MIN | 13 |
| 2. Derek Stingley Jr, HOU | 12 | |
| 3. Devin Lloyd, JAX | 9 | |
| 4. Arnold Ebiketie, ATL | 8 | |
| 5. Andrew Booth Jr, MIN | 7 | |
| Sacks | Complete List | |
Aidan Hutchinson
|
1. Aidan Hutchinson, DET | 4 |
| 2. Travon Walker, JAX | 1 | |
| 3. Jermaine Johnson II, NYJ | 1 | |
| 4. JT Woods, LAC | 1 | |
| 5. Perrion Winfrey, CLE | 1 | |
| Interceptions | Complete List | |
Derek Stingley Jr
|
1. Derek Stingley Jr, HOU | 2 |
| 2. Andrew Booth Jr, MIN | 2 | |
| 3. Daxton Hill, CIN | 2 | |
| 4. Lewis Cine, MIN | 1 | |
| 5. Kyler Gordon, CHI | 1 | |