League Leaders - Offense
| Passing Yards | Complete List | |
Caleb Williams
|
1. Caleb Williams, CHI | 3836 |
| 2. Jayden Daniels, WAS | 3775 | |
| 3. Drake Maye, NE | 3411 | |
| 4. Bo Nix, DEN | 3256 | |
| 5. J.J. McCarthy, MIN | 250 | |
| Rushing Yards | Complete List | |
Jonathon Brooks
|
1. Jonathon Brooks, CAR | 863 |
| 2. Bucky Irving, TB | 752 | |
| 3. Braelon Allen, NYJ | 492 | |
| 4. Jayden Daniels, WAS | 448 | |
| 5. Caleb Williams, CHI | 405 | |
| Receiving Yards | Complete List | |
Marvin Harrison Jr
|
1. Marvin Harrison Jr, CHI | 1108 |
| 2. Adonai Mitchell, IND | 993 | |
| 3. Malik Nabers, NYG | 897 | |
| 4. Ladd McConkey, LAC | 888 | |
| 5. Brian Thomas Jr, JAX | 863 | |
League Leaders - Defense
| Tackles | Complete List | |
Edgerrin Cooper
|
1. Edgerrin Cooper, GB | 74 |
| 2. Omar Speights, LAR | 68 | |
| 3. Nate Wiggins, BAL | 63 | |
| 4. Kool-Aid McKinstry, NO | 57 | |
| 5. Tyler Nubin, NYG | 51 | |
| Sacks | Complete List | |
Laiatu Latu
|
1. Laiatu Latu, IND | 6 |
| 2. Dallas Turner, MIN | 5 | |
| 3. Jared Verse, LAR | 5 | |
| 4. Tyrice Knight, SEA | 4 | |
| 5. Chop Robinson, CHI | 3 | |
| Interceptions | Complete List | |
Quinyon Mitchell
|
1. Quinyon Mitchell, PHI | 6 |
| 2. Kamari Lassiter, HOU | 4 | |
| 3. Trevin Wallace, CAR | 4 | |
| 4. Mike Sainristil, WAS | 3 | |
| 5. Andru Phillips, NYG | 3 | |