League Leaders - Offense
| Passing Yards | Complete List | |
Damon Boone
|
1. Damon Boone, DET | 6259 |
| 2. Troy Robertson, NO | 4801 | |
| 3. Shedeur Sanders, TKY | 4547 | |
| 4. Shawn York, CIN | 4545 | |
| 5. Jordan Baker, PAR | 4444 | |
| Rushing Yards | Complete List | |
Kenneth Walker III
|
1. Kenneth Walker III, SEA | 1526 |
| 2. Rachaad White, TB | 1462 | |
| 3. Bijan Robinson, ATL | 1279 | |
| 4. Jonathan Taylor, IND | 1198 | |
| 5. Breece Hall, NYJ | 1125 | |
| Receiving Yards | Complete List | |
Jameson Williams
|
1. Jameson Williams, DET | 2217 |
| 2. Sam LaPorta, DET | 1461 | |
| 3. Jeff Robbins, NO | 1425 | |
| 4. Justin Jefferson, MIA | 1341 | |
| 5. Khalil Shakir, LV | 1328 | |
League Leaders - Defense
| Tackles | Complete List | |
Drew Sanders
|
1. Drew Sanders, DEN | 112 |
| 2. Daiyan Henley, ATL | 100 | |
| 3. Nick Bolton, KC | 98 | |
| 4. Patrick Queen, PIT | 97 | |
| 5. Payton Wilson, HST | 96 | |
| Sacks | Complete List | |
Aidan Hutchinson
|
1. Aidan Hutchinson, DET | 18 |
| 2. Devin Ramsay, WAS | 16 | |
| 3. Alex Highsmith, BAL | 16 | |
| 4. Ben Grant, BAL | 14 | |
| 5. Nick Bosa, SF | 14 | |
| Interceptions | Complete List | |
Max Melton
|
1. Max Melton, ARI | 8 |
| 2. Jeremiah Owusu-Koramoah, CLE | 8 | |
| 3. Randy Reese, TB | 8 | |
| 4. L'Jarius Sneed, DET | 8 | |
| 5. Justin McCain, IND | 7 | |