League Leaders - Offense
| Passing Yards | Complete List | |
Alexander Sharpton
|
1. Alexander Sharpton, CLE | 1673 |
| 2. George Cabrera, CIN | 1564 | |
| 3. Shanard Poole, ATL | 1439 | |
| 4. Stevie Rhodes, DAL | 847 | |
| 5. Gary Cooper, MIN | 0 | |
| Rushing Yards | Complete List | |
Nick Carruthers
|
1. Nick Carruthers, KC | 272 |
| 2. Shanard Poole, ATL | 68 | |
| 3. George Hodge, BUF | 65 | |
| 4. Jazzario Hagans, ATL | 54 | |
| 5. Stevie Rhodes, DAL | 48 | |
| Receiving Yards | Complete List | |
Peter Wayne
|
1. Peter Wayne, CAR | 401 |
| 2. Donald Driver, NYG | 291 | |
| 3. Steven Porter, CLE | 250 | |
| 4. Javon Walker, GB | 229 | |
| 5. Carl Floyd, LV | 196 | |
League Leaders - Defense
| Tackles | Complete List | |
Andrew McCann
|
1. Andrew McCann, NYG | 22 |
| 2. Gavin Jeffries, TEN | 16 | |
| 3. Evan Gore, CIN | 14 | |
| 4. Dejon Sapp, MIN | 12 | |
| 5. Quandre Williams, ANC | 11 | |
| Sacks | Complete List | |
Wayne Lambert
|
1. Wayne Lambert, TEN | 4 |
| 2. Barry Hillhouse, LAR | 2 | |
| 3. Gill Ford, LAR | 1 | |
| 4. Shaquille Gray, WAS | 1 | |
| 5. Eric Thomas, ANC | 1 | |
| Interceptions | Complete List | |
Quandre Williams
|
1. Quandre Williams, ANC | 3 |
| 2. DeAndre Burton, BUF | 2 | |
| 3. Mitch May, LV | 1 | |
| 4. Sam Shields, GB | 1 | |
| 5. Gavin Jeffries, TEN | 1 | |