League Leaders - Offense
| Passing Yards | Complete List | |
Malik Willis
|
1. Malik Willis, BUF | 2479 |
| 2. Bailey Zappe, NYG | 13 | |
| 3. Matt Corral, CLE | 5 | |
| 4. Sam Howell, PHI | 5 | |
| 5. Kenny Pickett, CIN | 0 | |
| Rushing Yards | Complete List | |
Breece Hall
|
1. Breece Hall, IND | 634 |
| 2. Kenneth Walker III, ARI | 336 | |
| 3. James Cook, PHI | 326 | |
| 4. Dameon Pierce, SEA | 290 | |
| 5. Malik Willis, BUF | 206 | |
| Receiving Yards | Complete List | |
George Pickens
|
1. George Pickens, GB | 1071 |
| 2. Jameson Williams, GB | 657 | |
| 3. Isaiah Likely, BUF | 518 | |
| 4. Jahan Dotson, CHI | 464 | |
| 5. Velus Jones Jr, BUF | 454 | |
League Leaders - Defense
| Tackles | Complete List | |
Devin Lloyd
|
1. Devin Lloyd, TB | 36 |
| 2. Trent McDuffie, LV | 30 | |
| 3. Jaquan Brisker, TB | 29 | |
| 4. Martin Emerson, ARI | 28 | |
| 5. Lewis Cine, CAR | 26 | |
| Sacks | Complete List | |
Travon Walker
|
1. Travon Walker, BUF | 6 |
| 2. Jermaine Johnson II, SF | 4 | |
| 3. Malcolm Rodriguez, CLE | 1 | |
| 4. Kyron Johnson, LAC | 1 | |
| 5. Dominique Robinson, SF | 1 | |
| Interceptions | Complete List | |
Kyle Hamilton
|
1. Kyle Hamilton, GB | 6 |
| 2. Sauce Gardner, CHI | 6 | |
| 3. Tariq Woolen, BUF | 5 | |
| 4. Rodney Thomas II, NE | 2 | |
| 5. Trent McDuffie, LV | 2 | |