League Leaders - Offense
| Passing Yards | Complete List | |
Bryce Young
|
1. Bryce Young, CAR | 7414 |
| 2. C.J. Stroud, GB | 5609 | |
| 3. Unknown Player, MIN | 5378 | |
| 4. Desmond Ridder, ATL | 5371 | |
| 5. Anthony Richardson, IND | 4566 | |
| Rushing Yards | Complete List | |
Kenneth Walker III
|
1. Kenneth Walker III, SEA | 2591 |
| 2. Dameon Pierce, HOU | 2079 | |
| 3. Unknown Player, CHI | 1437 | |
| 4. Isiah Pacheco, NE | 1407 | |
| 5. Devon Achane, MIA | 1302 | |
| Receiving Yards | Complete List | |
Tyquan Thornton
|
1. Tyquan Thornton, KC | 3403 |
| 2. Chris Olave, BAL | 1904 | |
| 3. Christian Watson, GB | 1847 | |
| 4. Quentin Johnston, LAC | 1806 | |
| 5. Unknown Player, MIN | 1536 | |
League Leaders - Defense
| Tackles | Complete List | |
Trent McDuffie
|
1. Trent McDuffie, CHI | 54 |
| 2. Unknown Player, ATL | 54 | |
| 3. Unknown Player, NE | 53 | |
| 4. Kyle Hamilton, CAR | 51 | |
| 5. Unknown Player, BAL | 50 | |
| Sacks | Complete List | |
Aidan Hutchinson
|
1. Aidan Hutchinson, DET | 19 |
| 2. Lukas Van Ness, GB | 17 | |
| 3. Kayvon Thibodeaux, NYG | 13 | |
| 4. Kyron Johnson, PHI | 11 | |
| 5. Unknown Player, BUF | 10 | |
| Interceptions | Complete List | |
Jaylen Watson
|
1. Jaylen Watson, KC | 35 |
| 2. Andrew Booth Jr, PIT | 12 | |
| 3. Nolan Turner, CAR | 11 | |
| 4. Unknown Player, LV | 11 | |
| 5. Joshua Williams, CAR | 10 | |