League Leaders - Offense
| Passing Yards | Complete List | |
Patrick Mahomes
|
1. Patrick Mahomes, KC | 8699 |
| 2. Bryce Young, CAR | 7414 | |
| 3. Deshaun Watson, PHI | 6599 | |
| 4. Jalen Hurts, CLE | 6419 | |
| 5. Joe Burrow, CIN | 6104 | |
| Rushing Yards | Complete List | |
Kenneth Walker III
|
1. Kenneth Walker III, SEA | 2591 |
| 2. Dameon Pierce, HOU | 2079 | |
| 3. Josh Jacobs, LV | 1578 | |
| 4. Unknown Player, CHI | 1437 | |
| 5. Isiah Pacheco, NE | 1407 | |
| Receiving Yards | Complete List | |
Quez Watkins
|
1. Quez Watkins, PHI | 3546 |
| 2. Tyquan Thornton, KC | 3403 | |
| 3. Kyle Pitts, ATL | 2059 | |
| 4. Chris Godwin, CAR | 1948 | |
| 5. Equanimeous St. Brown, LAR | 1916 | |
League Leaders - Defense
| Tackles | Complete List | |
Lavonte David
|
1. Lavonte David, TB | 91 |
| 2. Demario Davis, TB | 75 | |
| 3. Levi Wallace, TB | 67 | |
| 4. Shaq Thompson, ATL | 61 | |
| 5. Kyle Dugger, TB | 59 | |
| Sacks | Complete List | |
Danielle Hunter
|
1. Danielle Hunter, MIN | 32 |
| 2. Brian Burns, CAR | 26 | |
| 3. Chris Jones, KC | 22 | |
| 4. Khalil Mack, LAC | 22 | |
| 5. Aidan Hutchinson, DET | 19 | |
| Interceptions | Complete List | |
Jaylen Watson
|
1. Jaylen Watson, KC | 35 |
| 2. Justin Reid, KC | 22 | |
| 3. Minkah Fitzpatrick, PIT | 14 | |
| 4. Trevon Diggs, DAL | 14 | |
| 5. Amani Oruwariye, NYG | 13 | |