League Leaders - Offense
| Passing Yards | Complete List | |
Mike Vick
|
1. Mike Vick, DEN | 5435 |
| 2. Justin Herbert, LAC | 4752 | |
| 3. Dalton Hill, CAR | 4622 | |
| 4. Joe Burrow, BKN | 4533 | |
| 5. Lamar Jackson, ANC | 4091 | |
| Rushing Yards | Complete List | |
Marquis Horton
|
1. Marquis Horton, MIN | 1199 |
| 2. Jonathan Taylor, IND | 1169 | |
| 3. Jerry Roye, DAL | 1146 | |
| 4. Jahmyr Gibbs, DET | 1142 | |
| 5. Bijan Robinson, ATL | 873 | |
| Receiving Yards | Complete List | |
Tez Johnson
|
1. Tez Johnson, LAC | 2077 |
| 2. Logan Cox, LAC | 1537 | |
| 3. Isaac Bruce, BKN | 1323 | |
| 4. Deion Fitzsimmons, DEN | 1311 | |
| 5. J.T. Chumley, GB | 1287 | |
League Leaders - Defense
| Tackles | Complete List | |
Lynn Heyward
|
1. Lynn Heyward, NYG | 74 |
| 2. Fred Warner, ATL | 73 | |
| 3. Ben Hardwick, TEN | 70 | |
| 4. Grant Davidson, SEA | 68 | |
| 5. Jose Powe, SEA | 66 | |
| Sacks | Complete List | |
Tim Slade
|
1. Tim Slade, DAL | 14 |
| 2. Aidan Hutchinson, DET | 14 | |
| 3. Trey Hendrickson, BKN | 14 | |
| 4. Roman Claiborne, ANC | 13 | |
| 5. David James, DEN | 13 | |
| Interceptions | Complete List | |
Chris Harden
|
1. Chris Harden, DEN | 8 |
| 2. Alexander Alexander, PIT | 7 | |
| 3. Kerby Joseph, DET | 7 | |
| 4. Marshon Lattimore, DAL | 6 | |
| 5. Kam Chancellor, CAR | 6 | |