League Leaders - Offense
| Passing Yards | Complete List | |
Danny Gregory
|
1. Danny Gregory, SF | 3937 |
| 2. Dalip Jin, DAL | 3089 | |
| 3. Chris Preston, GB | 1439 | |
| 4. Michael Anderson, SEA | 1164 | |
| 5. Aaron Griffin, NYG | 550 | |
| Rushing Yards | Complete List | |
James Woods
|
1. James Woods, BUF | 1015 |
| 2. Donnell Killings, MIN | 867 | |
| 3. Maurice Jones-Drew, JAX | 306 | |
| 4. Danny Gregory, SF | 267 | |
| 5. Lamar Johnson, KC | 220 | |
| Receiving Yards | Complete List | |
Richard Goldsberry
|
1. Richard Goldsberry, BUF | 1400 |
| 2. David McGraw, JAX | 899 | |
| 3. Tevin Scruggs, WAS | 858 | |
| 4. Antoine Hall, NE | 838 | |
| 5. Jamison Stephenson, ATL | 667 | |
League Leaders - Defense
| Tackles | Complete List | |
LaMichael Sherrod
|
1. LaMichael Sherrod, NO | 55 |
| 2. Alphonso Cromartie, BAL | 52 | |
| 3. DaWann Fitzsimmons, CHI | 51 | |
| 4. Derrick McKee, NYG | 49 | |
| 5. Antwuan Hamilton, LAR | 49 | |
| Sacks | Complete List | |
Mitch Berry
|
1. Mitch Berry, SEA | 8 |
| 2. Montell Blaylock, CLE | 8 | |
| 3. Evan Byars, NYJ | 6 | |
| 4. Arthur Williams, TB | 1 | |
| 5. Bryce Allen, TB | 1 | |
| Interceptions | Complete List | |
Austin Burgess
|
1. Austin Burgess, SF | 4 |
| 2. Justin Saunders, CHI | 3 | |
| 3. Shaquille Long, TB | 3 | |
| 4. C.J. Fuller, ARI | 2 | |
| 5. DaWann Fitzsimmons, CHI | 2 | |