League Leaders - Offense
| Passing Yards | Complete List | |
Dak Prescott
|
1. Dak Prescott, DAL | 292 |
| 2. Justin Herbert, LAC | 189 | |
| 3. Tom Brady, TB | 178 | |
| 4. Trey Lance, SF | 151 | |
| 5. Justin Fields, CHI | 130 | |
| Rushing Yards | Complete List | |
Austin Ekeler
|
1. Austin Ekeler, LAC | 104 |
| 2. Ezekiel Elliott, DAL | 82 | |
| 3. Leonard Fournette, TB | 62 | |
| 4. David Montgomery, CHI | 57 | |
| 5. Josh Jacobs, LV | 28 | |
| Receiving Yards | Complete List | |
Chris Godwin
|
1. Chris Godwin, TB | 118 |
| 2. Deebo Samuel, SF | 89 | |
| 3. CeeDee Lamb, DAL | 86 | |
| 4. Gerald Everett, LAC | 82 | |
| 5. Michael Gallup, DAL | 71 | |
League Leaders - Defense
| Tackles | Complete List | |
Shaquil Barrett
|
1. Shaquil Barrett, TB | 5 |
| 2. Jamel Dean, TB | 4 | |
| 3. Devin White, TB | 3 | |
| 4. Leighton Vander Esch, DAL | 3 | |
| 5. Tavon Young, CHI | 3 | |
| Sacks | Complete List | |
|
Shaquil Barrett
|
1. Shaquil Barrett, TB | 4 |
| 2. Joe Tryon-Shoyinka, TB | 1 | |
| 3. Armon Watts, CHI | 1 | |
| 4. Micah Parsons, DAL | 1 | |
| 5. Matthew Adams, CHI | 1 | |
| Interceptions | Complete List | |
Mike Edwards
|
1. Mike Edwards, TB | 2 |
| 2. Antoine Winfield Jr, TB | 2 | |
| 3. JC Jackson, LAC | 2 | |
| 4. Markquese Bell, DAL | 2 | |
| 5. Fred Warner, SF | 1 | |