League Leaders - Offense
| Passing Yards | Complete List | |
Trevor Lawrence
|
1. Trevor Lawrence, JAX | 6174 |
| 2. Sam Howell, WAS | 5824 | |
| 3. Theo Goldman, SEA | 5588 | |
| 4. Patrick Mahomes, LV | 5546 | |
| 5. Baker Mayfield, MIA | 5417 | |
| Rushing Yards | Complete List | |
Jonathan Taylor
|
1. Jonathan Taylor, IND | 2068 |
| 2. Breece Hall, NYJ | 1991 | |
| 3. Joe Mixon, NO | 1966 | |
| 4. James Cook, BUF | 1799 | |
| 5. Austin Ekeler, LAC | 1678 | |
| Receiving Yards | Complete List | |
Jameson Williams
|
1. Jameson Williams, JAX | 2524 |
| 2. Quez Watkins, JAX | 2261 | |
| 3. D.K. Metcalf, SEA | 2252 | |
| 4. Mike Evans, TB | 2160 | |
| 5. Jaylen Waddle, MIA | 2066 | |
League Leaders - Defense
| Tackles | Complete List | |
Troy Andersen
|
1. Troy Andersen, ATL | 71 |
| 2. A.J. Terrell Jr, CAR | 65 | |
| 3. Channing Tindall, CAR | 63 | |
| 4. Jaycee Horn, CAR | 59 | |
| 5. Greg Newsome II, CAR | 55 | |
| Sacks | Complete List | |
T.J. Watt
|
1. T.J. Watt, PIT | 30 |
| 2. Nick Bosa, SF | 24 | |
| 3. Kayvon Thibodeaux, NYG | 22 | |
| 4. Myles Garrett, CAR | 21 | |
| 5. Courtney Adkins, ARI | 19 | |
| Interceptions | Complete List | |
Zaire Chamberlin
|
1. Zaire Chamberlin, LV | 17 |
| 2. Marshon Lattimore, PIT | 15 | |
| 3. Ashtyn Davis, NYJ | 15 | |
| 4. James Herron, WAS | 15 | |
| 5. Trevon Moehrig, WAS | 14 | |