League Leaders - Offense
| Passing Yards | Complete List | |
Patrick Mahomes
|
1. Patrick Mahomes, KC | 5866 |
| 2. Jayden Daniels, WAS | 5280 | |
| 3. Lamar Jackson, BAL | 5240 | |
| 4. Trevor Lawrence, JAX | 5130 | |
| 5. J.J. McCarthy, NE | 4961 | |
| Rushing Yards | Complete List | |
Monty Wolff
|
1. Monty Wolff, NYG | 1550 |
| 2. Isiah Pacheco, KC | 1375 | |
| 3. Breece Hall, NYJ | 1242 | |
| 4. Damien Bailey, NE | 1234 | |
| 5. Emmitt Smith, DAL | 1186 | |
| Receiving Yards | Complete List | |
Randy Moss
|
1. Randy Moss, NE | 2074 |
| 2. Darren James, ATL | 2047 | |
| 3. Xavier Worthy, KC | 1839 | |
| 4. Santana Moss, WAS | 1634 | |
| 5. Ja'Marr Chase, CIN | 1487 | |
League Leaders - Defense
| Tackles | Complete List | |
Matt McGraw
|
1. Matt McGraw, ARI | 101 |
| 2. Germaine Pratt, CIN | 98 | |
| 3. Nate Dickerson, DEN | 89 | |
| 4. William Reece, IND | 84 | |
| 5. Johnnie Casey, IND | 81 | |
| Sacks | Complete List | |
Ty Palmer
|
1. Ty Palmer, JAX | 18 |
| 2. Josh Hines-Allen, JAX | 15 | |
| 3. Derrick Thomas, KC | 15 | |
| 4. Howie Long, LV | 14 | |
| 5. Ty Mitchell, DET | 14 | |
| Interceptions | Complete List | |
Roquan Smith
|
1. Roquan Smith, BAL | 11 |
| 2. Ty Law, KC | 11 | |
| 3. Johnny Groves, CAR | 11 | |
| 4. Jaden Hicks, KC | 10 | |
| 5. L'Jarius Sneed, TEN | 9 | |