League Leaders - Offense
| Passing Yards | Complete List | |
J.J. McCarthy
|
1. J.J. McCarthy, MIN | 3651 |
| 2. Drake Maye, NE | 3377 | |
| 3. Will Levis, TEN | 3213 | |
| 4. Bryce Young, CAR | 3124 | |
| 5. C.J. Stroud, HOU | 3106 | |
| Rushing Yards | Complete List | |
Bijan Robinson
|
1. Bijan Robinson, ATL | 1150 |
| 2. Jonathon Brooks, CAR | 1016 | |
| 3. De'Von Achane, MIA | 807 | |
| 4. Jahmyr Gibbs, DET | 807 | |
| 5. Caleb Williams, CHI | 736 | |
| Receiving Yards | Complete List | |
Rashee Rice
|
1. Rashee Rice, KC | 1440 |
| 2. Jordan Addison, MIN | 1036 | |
| 3. Puka Nacua, LAR | 959 | |
| 4. Marvin Harrison Jr, ARI | 891 | |
| 5. Michael Wilson, ARI | 833 | |
League Leaders - Defense
| Tackles | Complete List | |
Junior Colson
|
1. Junior Colson, LAC | 91 |
| 2. Edgerrin Cooper, GB | 84 | |
| 3. Trenton Simpson, BAL | 76 | |
| 4. Terrion Arnold, DET | 72 | |
| 5. Mekhi Blackmon, MIN | 70 | |
| Sacks | Complete List | |
Dallas Turner
|
1. Dallas Turner, MIN | 10 |
| 2. Byron Young, LAR | 7 | |
| 3. Jared Verse, LAR | 5 | |
| 4. Ruke *****horo, ATL | 4 | |
| 5. BJ Ojulari, ARI | 4 | |
| Interceptions | Complete List | |
Joey Porter
|
1. Joey Porter, PIT | 6 |
| 2. Chamarri Conner, KC | 4 | |
| 3. Nate Wiggins, BAL | 2 | |
| 4. Zach King, LV | 2 | |
| 5. Edgerrin Cooper, GB | 2 | |