League Leaders - Offense
| Passing Yards | Complete List | |
Joe Burrow
|
1. Joe Burrow, CIN | 4675 |
| 2. C.J. Stroud, HOU | 4401 | |
| 3. Josh Allen, BUF | 4331 | |
| 4. Drake Maye, NE | 4308 | |
| 5. Dak Prescott, DAL | 4209 | |
| Rushing Yards | Complete List | |
Jaleel McLaughlin
|
1. Jaleel McLaughlin, GB | 1446 |
| 2. Breece Hall, NYJ | 1395 | |
| 3. Glen Bigsby, NE | 1304 | |
| 4. Heath Porter, LV | 1237 | |
| 5. Keaton Mitchell, NO | 1233 | |
| Receiving Yards | Complete List | |
CeeDee Lamb
|
1. CeeDee Lamb, DAL | 1558 |
| 2. D.J. Moore, CHI | 1439 | |
| 3. Ja'Marr Chase, CIN | 1413 | |
| 4. Malik Nabers, NYG | 1232 | |
| 5. Stefon Diggs, HOU | 1163 | |
League Leaders - Defense
| Tackles | Complete List | |
Tremaine Edmunds
|
1. Tremaine Edmunds, CHI | 87 |
| 2. Austin Haywood, CHI | 81 | |
| 3. Trevin Wallace, CAR | 78 | |
| 4. Jordyn Brooks, MIA | 77 | |
| 5. Drew Sanders, DEN | 76 | |
| Sacks | Complete List | |
Micah Parsons
|
1. Micah Parsons, DAL | 19 |
| 2. Aaron Holmes, LAC | 16 | |
| 3. Marshawn Kneeland, DAL | 15 | |
| 4. Jaelan Phillips, NO | 14 | |
| 5. Jonathan Allen, CHI | 14 | |
| Interceptions | Complete List | |
Trevon Diggs
|
1. Trevon Diggs, DAL | 8 |
| 2. Dillon Clemons, NYG | 7 | |
| 3. Jartavius Martin, WAS | 6 | |
| 4. Justin Reid, WAS | 6 | |
| 5. Tyrel Dodson, WAS | 5 | |