League Leaders - Offense
| Passing Yards | Complete List | |
Caleb Williams
|
1. Caleb Williams, LV | 1359 |
| 2. Takio Jones, CIN | 1270 | |
| 3. Drake Maye, MIA | 920 | |
| 4. Bo Nix, TB | 837 | |
| 5. Quinn Ewers, LAR | 829 | |
| Rushing Yards | Complete List | |
|
Blake Corum
|
1. Blake Corum, MEX | 1093 |
| 2. TreVeyon Henderson, GB | 393 | |
| 3. Frank Gore Jr., HST | 116 | |
| 4. Donovan Edwards, LAC | 76 | |
| 5. Will E Beamon, MEX | 67 | |
| Receiving Yards | Complete List | |
Marvin Harrison Jr.
|
1. Marvin Harrison Jr., LV | 534 |
| 2. Blake Corum, MEX | 288 | |
| 3. Xavier Worthy, CIN | 253 | |
| 4. Emeka Egbuka, DUB | 228 | |
| 5. Brock Bowers, GB | 145 | |
League Leaders - Defense
| Tackles | Complete List | |
Kamren Kinchens
|
1. Kamren Kinchens, DAL | 17 |
| 2. Junior Colson, HOU | 16 | |
| 3. Mike Sainristil, TB | 15 | |
| 4. Everette Ellerbe, WAS | 15 | |
| 5. Calen Bullock, LV | 13 | |
| Sacks | Complete List | |
J.T. Tuimoloau
|
1. J.T. Tuimoloau, BAL | 4 |
| 2. Leonard Taylor III, LAR | 4 | |
| 3. Adisa Isaac, BAL | 2 | |
| 4. Barrett Carter, JAX | 2 | |
| 5. Michael Hall Jr., SEA | 2 | |
| Interceptions | Complete List | |
Deshawn Pace
|
1. Deshawn Pace, KC | 4 |
| 2. James Williams, SDG | 3 | |
| 3. Malachi Moore, IND | 3 | |
| 4. Javon Bullard, BUF | 3 | |
| 5. Cooper DeJean, GB | 2 | |