League Leaders - Offense
| Passing Yards | Complete List | |
JaMarcus Russell Jr
|
1. JaMarcus Russell Jr, IND | 4635 |
| 2. Callum Whitfield, DAL | 4136 | |
| 3. Sterling Archer, NE | 3039 | |
| 4. Shane Coleman, WAS | 2300 | |
| 5. Brett Favre II, DEN | 1299 | |
| Rushing Yards | Complete List | |
Joe Smart
|
1. Joe Smart, BUF | 489 |
| 2. Rudy Ellis, LV | 410 | |
| 3. Spencer Flowers, KC | 277 | |
| 4. Callum Whitfield, DAL | 234 | |
| 5. Sterling Archer, NE | 210 | |
| Receiving Yards | Complete List | |
Eric Whitehead
|
1. Eric Whitehead, DAL | 1281 |
| 2. DeSean Dean, SEA | 1025 | |
| 3. Stephen Bright, MIA | 969 | |
| 4. Chris Wood, DAL | 584 | |
| 5. Adam McMahon, TEN | 554 | |
League Leaders - Defense
| Tackles | Complete List | |
Marlon Cole
|
1. Marlon Cole, NYJ | 38 |
| 2. Grant Irvin, MIN | 34 | |
| 3. D'Andre Calhoun, IND | 31 | |
| 4. Rayshon Lippett, NO | 28 | |
| 5. Erik Perry, SF | 27 | |
| Sacks | Complete List | |
Rashaad Robinson
|
1. Rashaad Robinson, NE | 6 |
| 2. Rayshon Lippett, NO | 6 | |
| 3. Kevin Overstreet, IND | 4 | |
| 4. Deron Larson, HOU | 4 | |
| 5. Tony Walden, NE | 3 | |
| Interceptions | Complete List | |
Julius Duckworth
|
1. Julius Duckworth, NYJ | 9 |
| 2. D'Andre Calhoun, IND | 9 | |
| 3. Brian Sample, DAL | 4 | |
| 4. Kemani Hodges, PHI | 4 | |
| 5. Charles Samuel, DAL | 4 | |