League Leaders - Offense
| Passing Yards | Complete List | |
Daniel Jones
|
1. Daniel Jones, NYG | 4254 |
| 2. Zach Wilson, NYJ | 3751 | |
| 3. Malik Willis, TEN | 3660 | |
| 4. Davis Mills, LV | 3617 | |
| 5. Joe Burrow, CIN | 3519 | |
| Rushing Yards | Complete List | |
Alvin Kamara
|
1. Alvin Kamara, KC | 2181 |
| 2. Saquon Barkley, NYG | 1434 | |
| 3. Jonathan Taylor, IND | 1211 | |
| 4. Isaiah Fleming, BAL | 1162 | |
| 5. Tony Pollard, DAL | 1100 | |
| Receiving Yards | Complete List | |
Odell Beckham Jr
|
1. Odell Beckham Jr, NYG | 2341 |
| 2. Elijah Moore, NYJ | 1480 | |
| 3. Parker McKay, SEA | 1346 | |
| 4. Jameson Williams, DET | 1329 | |
| 5. Travis Kelce, KC | 1239 | |
League Leaders - Defense
| Tackles | Complete List | |
Jordan Hicks
|
1. Jordan Hicks, MIN | 60 |
| 2. Matt Milano, BUF | 57 | |
| 3. Kaden Elliss, CHI | 55 | |
| 4. Kevin Way, CIN | 46 | |
| 5. Deion Jones, CLE | 43 | |
| Sacks | Complete List | |
Von Miller
|
1. Von Miller, BUF | 16 |
| 2. Azeez Ojulari, NYG | 14 | |
| 3. Chandler Jones, LV | 14 | |
| 4. Demario Davis, NYG | 12 | |
| 5. Micah Parsons, DAL | 12 | |
| Interceptions | Complete List | |
Kevin Byard
|
1. Kevin Byard, TEN | 16 |
| 2. Stephon Gilmore, NYG | 15 | |
| 3. Trevon Diggs, DAL | 13 | |
| 4. Xavier McKinney, NYG | 10 | |
| 5. Juan Thornhill, KC | 9 | |