League Leaders - Offense
| Passing Yards | Complete List | |
Jalen Milroe
|
1. Jalen Milroe, DAL | 3323 |
| 2. Shedeur Sanders, JAX | 1760 | |
| 3. Drew Allar, NO | 1368 | |
| 4. Quinn Ewers, CLE | 660 | |
| 5. Dillon Gabriel, HOU | 446 | |
| Rushing Yards | Complete List | |
TreVeyon Henderson
|
1. TreVeyon Henderson, LAR | 652 |
| 2. Jalen Milroe, DAL | 358 | |
| 3. Ollie Gordon, CHI | 191 | |
| 4. Unknown Player, SF | 162 | |
| 5. Jamarion Miller, SEA | 152 | |
| Receiving Yards | Complete List | |
Tetairoa McMillian
|
1. Tetairoa McMillian, KC | 674 |
| 2. Emeka Egbuka, GB | 593 | |
| 3. Luther Burden III, CLE | 526 | |
| 4. Evan Stewart, DET | 429 | |
| 5. Jalen Rager, DEN | 350 | |
League Leaders - Defense
| Tackles | Complete List | |
Jamon Dumas-Johnson
|
1. Jamon Dumas-Johnson, IND | 36 |
| 2. Will Johnson, ARI | 26 | |
| 3. Travis Hunter, IND | 26 | |
| 4. Davison Igbinosun, BAL | 24 | |
| 5. Denzel Burke, MIA | 24 | |
| Sacks | Complete List | |
Khordae Sydnor
|
1. Khordae Sydnor, BAL | 5 |
| 2. David Bailey, HOU | 5 | |
| 3. Dasan McCullough, LAC | 3 | |
| 4. Will Johnson, ARI | 3 | |
| 5. Jack Sawyer, DEN | 3 | |
| Interceptions | Complete List | |
Andrew Mukuba
|
1. Andrew Mukuba, MIA | 8 |
| 2. Zion Branch, IND | 5 | |
| 3. Sonny Styles, BAL | 4 | |
| 4. Billy Bowman Jr., LAR | 3 | |
| 5. Travis Hunter, IND | 3 | |