League Leaders - Offense
| Passing Yards | Complete List | |
Carson Wentz
|
1. Carson Wentz, BUF | 367 |
| 2. Lamar Jackson, SF | 347 | |
| 3. Josh Allen, LV | 344 | |
| 4. Davis Mills, BAL | 339 | |
| 5. Dustin Booth, ATL | 324 | |
| Rushing Yards | Complete List | |
Nick Chubb
|
1. Nick Chubb, PIT | 119 |
| 2. Joe Mixon, GB | 108 | |
| 3. J.K. Dobbins, CLE | 107 | |
| 4. Breece Hall, TB | 97 | |
| 5. Najee Harris, DAL | 95 | |
| Receiving Yards | Complete List | |
D.K. Metcalf
|
1. D.K. Metcalf, NYG | 196 |
| 2. Terry McLaurin, JAX | 153 | |
| 3. CeeDee Lamb, NYJ | 148 | |
| 4. Justin Jefferson, BAL | 146 | |
| 5. Evan McFadden, DEN | 140 | |
League Leaders - Defense
| Tackles | Complete List | |
Shaun Webber
|
1. Shaun Webber, IND | 10 |
| 2. Darnay Holmes, SF | 9 | |
| 3. Miles Langley, KC | 9 | |
| 4. Chase Young, LV | 9 | |
| 5. Trevor Brayton, CIN | 8 | |
| Sacks | Complete List | |
Randy McCullough
|
1. Randy McCullough, CIN | 3 |
| 2. Aidan Hutchinson, CLE | 2 | |
| 3. Micheal Clemons, CLE | 2 | |
| 4. Marcus Davenport, KC | 2 | |
| 5. Kenny Clark, ARI | 2 | |
| Interceptions | Complete List | |
L'Jarius Sneed
|
1. L'Jarius Sneed, PIT | 2 |
| 2. A.J. Terrell Jr, SF | 1 | |
| 3. Shaquil Barrett, SF | 1 | |
| 4. Marquise Benson, DEN | 1 | |
| 5. Logan Wilson, SF | 1 | |