League Leaders - Offense
| Passing Yards | Complete List | |
Trevor Lawrence
|
1. Trevor Lawrence, JAX | 2278 |
| 2. Mark Bishop, ARI | 2142 | |
| 3. Jalen Hurts, PHI | 1904 | |
| 4. Anthony Richardson, IND | 1840 | |
| 5. C.J. Stroud, ORL | 1789 | |
| Rushing Yards | Complete List | |
Bijan Robinson
|
1. Bijan Robinson, ATL | 866 |
| 2. James Cook, BUF | 829 | |
| 3. Josh Jacobs, GB | 804 | |
| 4. Jonathan Taylor, IND | 703 | |
| 5. Bucky Irving, TB | 657 | |
| Receiving Yards | Complete List | |
Brian Thomas Jr
|
1. Brian Thomas Jr, JAX | 899 |
| 2. Marvin Harrison Jr, ARI | 845 | |
| 3. Daniel Bellinger, IND | 689 | |
| 4. Cole Kmet, CHI | 675 | |
| 5. Isaiah Bolden, TB | 666 | |
League Leaders - Defense
| Tackles | Complete List | |
Conner Murphy
|
1. Conner Murphy, BKN | 30 |
| 2. Jevon Holland, JAX | 29 | |
| 3. Zack Baun, PHI | 28 | |
| 4. Nakobe Dean, PHI | 27 | |
| 5. Henry Hutton, JAX | 25 | |
| Sacks | Complete List | |
Dexter Lawrence II
|
1. Dexter Lawrence II, BKN | 8 |
| 2. Andrew Van Ginkel, MIN | 6 | |
| 3. Dorian Crowley, CLE | 6 | |
| 4. Montez Sweat, CHI | 5 | |
| 5. Vernon Boston, CHI | 5 | |
| Interceptions | Complete List | |
Antoine Winfield Jr
|
1. Antoine Winfield Jr, TB | 6 |
| 2. DaRon Bland, GB | 4 | |
| 3. Bobby Okereke, BKN | 4 | |
| 4. Tyrel Dodson, TB | 3 | |
| 5. Marshon Lattimore, WAS | 3 | |