League Leaders - Offense
| Passing Yards | Complete List | |
Mark Bishop
|
1. Mark Bishop, ARI | 1834 |
| 2. Trevor Lawrence, JAX | 1824 | |
| 3. C.J. Stroud, ORL | 1661 | |
| 4. Jalen Hurts, PHI | 1406 | |
| 5. Joe Burrow, CIN | 1267 | |
| Rushing Yards | Complete List | |
Josh Jacobs
|
1. Josh Jacobs, GB | 712 |
| 2. James Cook, BUF | 665 | |
| 3. Bijan Robinson, ATL | 660 | |
| 4. Trevon Franklin, ARI | 553 | |
| 5. Chase Brown, CHI | 457 | |
| Receiving Yards | Complete List | |
Marvin Harrison Jr
|
1. Marvin Harrison Jr, ARI | 756 |
| 2. Brian Thomas Jr, JAX | 736 | |
| 3. Michael Santiago, PHI | 506 | |
| 4. Ja'Marr Chase, CIN | 504 | |
| 5. Cole Kmet, CHI | 486 | |
League Leaders - Defense
| Tackles | Complete List | |
Jevon Holland
|
1. Jevon Holland, JAX | 23 |
| 2. Zack Baun, PHI | 23 | |
| 3. Nakobe Dean, PHI | 18 | |
| 4. Jack Campbell, DET | 18 | |
| 5. Jeremy Chinn, IND | 17 | |
| Sacks | Complete List | |
Andrew Van Ginkel
|
1. Andrew Van Ginkel, MIN | 6 |
| 2. Vernon Boston, CHI | 5 | |
| 3. Dorian Crowley, CLE | 5 | |
| 4. Montez Sweat, CHI | 4 | |
| 5. Chris Grove, PHI | 4 | |
| Interceptions | Complete List | |
Antoine Winfield Jr
|
1. Antoine Winfield Jr, TB | 6 |
| 2. DaRon Bland, GB | 4 | |
| 3. Kyler Gordon, CHI | 3 | |
| 4. Marshon Lattimore, WAS | 3 | |
| 5. Tyrel Dodson, TB | 3 | |