League Leaders - Offense
| Passing Yards | Complete List | |
Darren Curran
|
1. Darren Curran, CIN | 3910 |
| 2. Josh Allen, BUF | 3817 | |
| 3. Patrick Mahomes, KC | 3745 | |
| 4. Michael Penix Jr, ATL | 3723 | |
| 5. Charles Lincoln, DAL | 3673 | |
| Rushing Yards | Complete List | |
Manny Kramer
|
1. Manny Kramer, ARI | 1430 |
| 2. Brian Truman, DET | 1017 | |
| 3. Harvey Muldrow, MIN | 969 | |
| 4. Isiah Pacheco, KC | 915 | |
| 5. Travis Etienne Jr, JAX | 906 | |
| Receiving Yards | Complete List | |
Darren James
|
1. Darren James, ATL | 1543 |
| 2. Andre Reed, BUF | 1112 | |
| 3. Terrell Owens, DAL | 1107 | |
| 4. Brennan Presley, TEN | 1028 | |
| 5. Randy Moss, NE | 1023 | |
League Leaders - Defense
| Tackles | Complete List | |
Junior Seau
|
1. Junior Seau, LAC | 75 |
| 2. Fred Warner, SF | 67 | |
| 3. Derrick Brooks, TB | 66 | |
| 4. Tremaine Edmunds, CHI | 63 | |
| 5. Kyle Kitchens, IND | 61 | |
| Sacks | Complete List | |
Myles Garrett
|
1. Myles Garrett, CLE | 17 |
| 2. Chris Doleman, MIN | 16 | |
| 3. Bernie Culliver, BAL | 15 | |
| 4. Bruce Smith, BUF | 15 | |
| 5. T.J. Watt, PIT | 14 | |
| Interceptions | Complete List | |
Dax Hill
|
1. Dax Hill, CIN | 13 |
| 2. Jaden Hicks, KC | 12 | |
| 3. Calen Bullock, HOU | 12 | |
| 4. Jamal Adams, DET | 8 | |
| 5. David Weston, CAR | 8 | |