League Leaders - Offense
| Passing Yards | Complete List | |
Sam Howell
|
1. Sam Howell, WAS | 2027 |
| 2. Desmond Ridder, ATL | 1754 | |
| 3. Malik Willis, TEN | 1698 | |
| 4. Kenny Pickett, PIT | 1600 | |
| 5. Matt Corral, CAR | 1252 | |
| Rushing Yards | Complete List | |
James Cook
|
1. James Cook, BUF | 752 |
| 2. Zamir White, LV | 652 | |
| 3. Kenneth Walker III, SEA | 512 | |
| 4. Malik Willis, TEN | 313 | |
| 5. Isiah Pacheco, KC | 298 | |
| Receiving Yards | Complete List | |
Jameson Williams
|
1. Jameson Williams, DET | 625 |
| 2. Breece Hall, NYJ | 619 | |
| 3. Velus Jones Jr, CHI | 544 | |
| 4. Alec Pierce, IND | 401 | |
| 5. Trey McBride, ARI | 357 | |
League Leaders - Defense
| Tackles | Complete List | |
Christian Harris
|
1. Christian Harris, HOU | 23 |
| 2. Jaquan Brisker, CHI | 23 | |
| 3. Nakobe Dean, PHI | 22 | |
| 4. Lewis Cine, MIN | 21 | |
| 5. Kyler Gordon, CHI | 20 | |
| Sacks | Complete List | |
Devonte Wyatt
|
1. Devonte Wyatt, GB | 7 |
| 2. Troy Andersen, ATL | 6 | |
| 3. Aidan Hutchinson, DET | 4 | |
| 4. Nik Bonitto, DEN | 3 | |
| 5. Cam Taylor-Britt, CIN | 3 | |
| Interceptions | Complete List | |
Bubba Bolden
|
1. Bubba Bolden, WAS | 8 |
| 2. Daxton Hill, CIN | 7 | |
| 3. Damarri Mathis, DEN | 6 | |
| 4. Jaquan Brisker, CHI | 5 | |
| 5. Nazeeh Johnson, KC | 5 | |