League Leaders - Offense
| Passing Yards | Complete List | |
Aaron Rodgers
|
1. Aaron Rodgers, NYJ | 1961 |
| 2. Joe Burrow, CIN | 1538 | |
| 3. Justin Herbert, LAC | 1506 | |
| 4. C.J. Stroud, HOU | 1461 | |
| 5. Josh Allen, BUF | 1432 | |
| Rushing Yards | Complete List | |
Kenneth Walker III
|
1. Kenneth Walker III, SEA | 1511 |
| 2. Tony Pollard, DAL | 1466 | |
| 3. Josh Jacobs, LV | 1418 | |
| 4. Aaron Jones, GB | 1308 | |
| 5. Austin Ekeler, LAC | 1293 | |
| Receiving Yards | Complete List | |
Ja'Marr Chase
|
1. Ja'Marr Chase, CIN | 1170 |
| 2. Justin Jefferson, MIN | 1137 | |
| 3. Garrett Wilson, NYJ | 938 | |
| 4. Unknown Player, BAL | 923 | |
| 5. Tyreek Hill, MIA | 901 | |
League Leaders - Defense
| Tackles | Complete List | |
Demario Davis
|
1. Demario Davis, NO | 48 |
| 2. Isaiah Simmons, ARI | 47 | |
| 3. Deion Jones, CAR | 46 | |
| 4. Devin White, TB | 45 | |
| 5. Derwin James Jr, LAC | 43 | |
| Sacks | Complete List | |
Micah Parsons
|
1. Micah Parsons, DAL | 9 |
| 2. Lorenzo Carter, ATL | 9 | |
| 3. Jonathan Allen, WAS | 8 | |
| 4. Arnold Ebiketie, ATL | 8 | |
| 5. Myles Garrett, CLE | 7 | |
| Interceptions | Complete List | |
Minkah Fitzpatrick
|
1. Minkah Fitzpatrick, PIT | 9 |
| 2. Adrian Amos, NYJ | 9 | |
| 3. Justin Simmons, DEN | 8 | |
| 4. Grant Delpit, PHI | 7 | |
| 5. Jonathan Jones, NE | 7 | |