League Leaders - Offense
| Passing Yards | Complete List | |
Lamar Jackson
|
1. Lamar Jackson, LAC | 3437 |
| 2. Bo Nix, KC | 3045 | |
| 3. Caleb Williams, SF | 3034 | |
| 4. Patrick Mahomes, TOR | 2881 | |
| 5. Joe Burrow, NE | 2628 | |
| Rushing Yards | Complete List | |
Jahmyr Gibbs
|
1. Jahmyr Gibbs, WAS | 831 |
| 2. Trey Benson, PHI | 752 | |
| 3. Chuba Hubbard, MIA | 717 | |
| 4. Najee Harris, NE | 629 | |
| 5. Nick Chubb, ATL | 609 | |
| Receiving Yards | Complete List | |
Richard Church
|
1. Richard Church, TOR | 1171 |
| 2. Calvin Ridley, LAC | 1031 | |
| 3. Brock Bowers, NYG | 1018 | |
| 4. Marvin Harrison Jr, SF | 939 | |
| 5. Saul Bond, LAR | 924 | |
League Leaders - Defense
| Tackles | Complete List | |
Germaine Pratt
|
1. Germaine Pratt, MIN | 43 |
| 2. C.J. Mosley, IND | 42 | |
| 3. Zack Baun, PIT | 42 | |
| 4. Fred Warner, KC | 41 | |
| 5. Shaquill Griffin, BUF | 40 | |
| Sacks | Complete List | |
Micah Parsons
|
1. Micah Parsons, LV | 17 |
| 2. Myles Garrett, KC | 13 | |
| 3. Derick Hall, NYG | 10 | |
| 4. Montez Sweat, WAS | 10 | |
| 5. Danielle Hunter, CHI | 10 | |
| Interceptions | Complete List | |
Denzel Ward
|
1. Denzel Ward, LAR | 8 |
| 2. Derek Stingley Jr, NYG | 6 | |
| 3. L'Jarius Sneed, LAR | 6 | |
| 4. Foyesade Oluokun, ARI | 6 | |
| 5. Payton Wilson, LV | 6 | |