League Leaders - Offense
| Passing Yards | Complete List | |
Matthew Stafford
|
1. Matthew Stafford, LAR | 4603 |
| 2. Trevor Lawrence, JAX | 4460 | |
| 3. Jaxson Dart, NYG | 4384 | |
| 4. Patrick Mahomes, KC | 4278 | |
| 5. Aaron Rodgers, PIT | 4269 | |
| Rushing Yards | Complete List | |
Ashton Jeanty
|
1. Ashton Jeanty, LV | 1240 |
| 2. Josh Jacobs, GB | 1210 | |
| 3. Saquon Barkley, PHI | 1162 | |
| 4. Joe Mixon, HOU | 1045 | |
| 5. Bijan Robinson, MIN | 1037 | |
| Receiving Yards | Complete List | |
Tyreek Hill
|
1. Tyreek Hill, ATL | 1856 |
| 2. Puka Nacua, LAR | 1828 | |
| 3. Xavier Worthy, KC | 1470 | |
| 4. Anthony Schwartz, IND | 1441 | |
| 5. Cooper Kupp, SEA | 1378 | |
League Leaders - Defense
| Tackles | Complete List | |
Emmett Sellers
|
1. Emmett Sellers, DET | 85 |
| 2. Demario Davis, NO | 77 | |
| 3. Cassius Perriman, TEN | 75 | |
| 4. Daiyan Henley, LAC | 74 | |
| 5. Troy Andersen, ATL | 72 | |
| Sacks | Complete List | |
Alex Highsmith
|
1. Alex Highsmith, TB | 21 |
| 2. Abdul Carter, NYG | 17 | |
| 3. T.J. Watt, PIT | 17 | |
| 4. Aidan Hutchinson, DET | 16 | |
| 5. Brian Burns, NYG | 15 | |
| Interceptions | Complete List | |
Jack Jones
|
1. Jack Jones, LAR | 10 |
| 2. Quentin Lake, LAR | 10 | |
| 3. Travis Hunter, JAX | 10 | |
| 4. Marshon Lattimore, WAS | 9 | |
| 5. Omar Speights, LAR | 8 | |