League Leaders - Offense
| Passing Yards | Complete List | |
Russell Wilson
|
1. Russell Wilson, DEN | 1788 |
| 2. Dak Prescott, DAL | 1683 | |
| 3. Kyler Murray, ARI | 1676 | |
| 4. Ryne Doulong, TB | 1666 | |
| 5. Patrick Mahomes, KC | 1631 | |
| Rushing Yards | Complete List | |
Nick Chubb
|
1. Nick Chubb, CLE | 911 |
| 2. Jonathan Taylor, IND | 715 | |
| 3. Kenneth Walker III, SEA | 714 | |
| 4. J.K. Dobbins, BAL | 708 | |
| 5. Alvin Kamara, NO | 617 | |
| Receiving Yards | Complete List | |
Luke Breaston
|
1. Luke Breaston, DAL | 747 |
| 2. Cooper Kupp, LAR | 687 | |
| 3. D.K. Metcalf, SEA | 652 | |
| 4. JC Kaballo, KC | 646 | |
| 5. Calvin Austin III, PIT | 626 | |
League Leaders - Defense
| Tackles | Complete List | |
Logan Wilson
|
1. Logan Wilson, CIN | 50 |
| 2. Bobby Wagner, LAR | 46 | |
| 3. Divine Deablo, LV | 43 | |
| 4. De'Vondre Campbell, GB | 41 | |
| 5. Akeem Davis-Gaither, CIN | 39 | |
| Sacks | Complete List | |
Micah Parsons
|
1. Micah Parsons, DAL | 10 |
| 2. Myles Garrett, CLE | 10 | |
| 3. Chris Jones, KC | 9 | |
| 4. Von Miller, BUF | 8 | |
| 5. Chase Young, WAS | 8 | |
| Interceptions | Complete List | |
Cole Holcomb
|
1. Cole Holcomb, WAS | 8 |
| 2. Jevon Holland, MIA | 7 | |
| 3. Nick Cross, IND | 7 | |
| 4. Budda Baker, ARI | 6 | |
| 5. Greedy Williams, CLE | 6 | |