League Leaders - Offense
| Passing Yards | Complete List | |
Dak Prescott
|
1. Dak Prescott, SDG | 1588 |
| 2. Kenny Pickett, PIT | 1406 | |
| 3. Patrick Mahomes, KC | 1396 | |
| 4. Caleb Williams, LV | 1359 | |
| 5. Will Levis, TEN | 1290 | |
| Rushing Yards | Complete List | |
Blake Corum
|
1. Blake Corum, MEX | 1093 |
| 2. Jahmyr Gibbs, DET | 635 | |
| 3. Najee Harris, PIT | 631 | |
| 4. Ryan Jones, CIN | 613 | |
| 5. Nick Chubb, CLE | 563 | |
| Receiving Yards | Complete List | |
Jordan Addison
|
1. Jordan Addison, TEN | 543 |
| 2. Marvin Harrison Jr., LV | 534 | |
| 3. Kadarius Toney, KC | 440 | |
| 4. K.J. Hamler, KC | 428 | |
| 5. Bo Melton, NYJ | 385 | |
League Leaders - Defense
| Tackles | Complete List | |
Bobby Okereke
|
1. Bobby Okereke, NYG | 29 |
| 2. Azeez Al-Shaair, WAS | 24 | |
| 3. Harold Landry III, TEN | 23 | |
| 4. Channing Tindall, MIA | 23 | |
| 5. Kamren Curl, WAS | 22 | |
| Sacks | Complete List | |
George Karlaftis
|
1. George Karlaftis, KC | 7 |
| 2. Jermaine Johnson II, NYJ | 6 | |
| 3. Shaquil Barrett, TB | 5 | |
| 4. Baron Browning, OAK | 5 | |
| 5. Myles Garrett, CLE | 5 | |
| Interceptions | Complete List | |
Kalon Barnes
|
1. Kalon Barnes, NYJ | 6 |
| 2. Kyle Dugger, MIA | 5 | |
| 3. Justin Reid, KC | 5 | |
| 4. Xavien Howard, MIA | 5 | |
| 5. Nick Bolton, KC | 4 | |