League Leaders - Offense
| Passing Yards | Complete List | |
Dak Prescott
|
1. Dak Prescott, DAL | 3147 |
| 2. Joe Burrow, CIN | 2669 | |
| 3. Bryce Young, MIN | 2516 | |
| 4. Trevor Lawrence, JAX | 2512 | |
| 5. Tua Tagovailoa, TB | 2451 | |
| Rushing Yards | Complete List | |
Kenneth Walker III
|
1. Kenneth Walker III, SEA | 1133 |
| 2. Joe Mixon, CIN | 1110 | |
| 3. Miles Sanders, PHI | 1017 | |
| 4. Clyde Edwards-Helaire, KC | 1008 | |
| 5. Nick Chubb, CLE | 873 | |
| Receiving Yards | Complete List | |
Ricky Mills
|
1. Ricky Mills, LAR | 1094 |
| 2. Justin Jefferson, MIN | 934 | |
| 3. Daniel Bellinger, NYG | 899 | |
| 4. Terry McLaurin, TB | 888 | |
| 5. Mecole Hardman, KC | 878 | |
League Leaders - Defense
| Tackles | Complete List | |
Troy Andersen
|
1. Troy Andersen, ATL | 64 |
| 2. C.J. Mosley, NYJ | 59 | |
| 3. Foyesade Oluokun, JAX | 48 | |
| 4. Eric Kendricks, MIN | 43 | |
| 5. Darius Leonard, IND | 42 | |
| Sacks | Complete List | |
Micah Parsons
|
1. Micah Parsons, DAL | 18 |
| 2. Von Miller, BUF | 10 | |
| 3. Azeez Ojulari, NYG | 9 | |
| 4. DeMarcus Lawrence, DAL | 8 | |
| 5. Jamiu Ojulari, SEA | 8 | |
| Interceptions | Complete List | |
Eddie Jackson
|
1. Eddie Jackson, CHI | 11 |
| 2. Jessie Bates III, CIN | 10 | |
| 3. Minkah Fitzpatrick, PIT | 9 | |
| 4. Patrick Surtain II, DEN | 8 | |
| 5. Eric Stokes, GB | 8 | |