League Leaders - Offense
| Passing Yards | Complete List | |
Jonathan Moxon
|
1. Jonathan Moxon, LV | 3273 |
| 2. Seth Robertson, NYG | 1021 | |
| 3. Justin Foster, LAR | 191 | |
| 4. Brian Wilber, BUF | 65 | |
| 5. Tyreke Martin, MIN | 39 | |
| Rushing Yards | Complete List | |
Chris Hannah
|
1. Chris Hannah, TB | 1277 |
| 2. Jonathan Moxon, LV | 494 | |
| 3. Julian White, NYG | 467 | |
| 4. John Kelley, TEN | 390 | |
| 5. C.J. Wilburn, DET | 227 | |
| Receiving Yards | Complete List | |
Charlie Tweeder
|
1. Charlie Tweeder, LV | 1229 |
| 2. Stevie Newell, BAL | 1155 | |
| 3. Darian Ellis, MIA | 1047 | |
| 4. Anquan Boldin II, ARI | 742 | |
| 5. George Woodard, TEN | 740 | |
League Leaders - Defense
| Tackles | Complete List | |
Dallas Nolan
|
1. Dallas Nolan, ATL | 54 |
| 2. Manny Woodard, TB | 49 | |
| 3. David Brown, SEA | 48 | |
| 4. Joey Bond, CLE | 48 | |
| 5. Pat Hill, IND | 46 | |
| Sacks | Complete List | |
Cris Elliott
|
1. Cris Elliott, DEN | 8 |
| 2. Andrew Collins, PIT | 8 | |
| 3. Isaac Wolfe, LV | 7 | |
| 4. Chauncey Jackson, LAC | 4 | |
| 5. Junior Hall, DEN | 3 | |
| Interceptions | Complete List | |
David Brown
|
1. David Brown, SEA | 6 |
| 2. Manny Woodard, TB | 5 | |
| 3. Matt Ferrell, TB | 3 | |
| 4. Tavon Britton, KC | 3 | |
| 5. Josh Dee, MIA | 3 | |