League Leaders - Offense
| Passing Yards | Complete List | |
Trevor Lawrence
|
1. Trevor Lawrence, JAX | 3755 |
| 2. Ben Schmitt, LV | 3152 | |
| 3. Delonte Bridges, NYG | 3135 | |
| 4. Brock Purdy, ATL | 3124 | |
| 5. Patrick Mahomes, KC | 2992 | |
| Rushing Yards | Complete List | |
Damion Anderson
|
1. Damion Anderson, PIT | 1257 |
| 2. Travis Etienne Jr, TB | 997 | |
| 3. P.J. Dickens, GB | 977 | |
| 4. Kenneth Walker III, WAS | 933 | |
| 5. Bijan Robinson, ATL | 894 | |
| Receiving Yards | Complete List | |
Jonathan Mingo
|
1. Jonathan Mingo, CAR | 1102 |
| 2. Joshua Donahue, JAX | 1068 | |
| 3. Dallas Goedert, NE | 992 | |
| 4. Kyle Pitts, ATL | 975 | |
| 5. Chigoziem Okonkwo, JAX | 898 | |
League Leaders - Defense
| Tackles | Complete List | |
Bobby Okereke
|
1. Bobby Okereke, LV | 49 |
| 2. Kenneth Murray Jr, ATL | 49 | |
| 3. James Cunningham, ATL | 47 | |
| 4. Nick Bolton, IND | 45 | |
| 5. Ernest Jones, LAR | 44 | |
| Sacks | Complete List | |
Lukas Van Ness
|
1. Lukas Van Ness, GB | 10 |
| 2. Antoine Nicks, GB | 10 | |
| 3. Luke Weaver, CLE | 10 | |
| 4. Jalen Carter, PHI | 9 | |
| 5. Kevin Gordon, CLE | 8 | |
| Interceptions | Complete List | |
Kevin Byard
|
1. Kevin Byard, GB | 8 |
| 2. Minkah Fitzpatrick, PIT | 8 | |
| 3. Christian Gonzalez, NE | 6 | |
| 4. Lindsey Patterson, ATL | 5 | |
| 5. Trevon Diggs, ARI | 5 | |